4-Methyl-2-oxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-5-carbaldehyde
نویسندگان
چکیده
In the title compound, C(11)H(12)N(2)O(2), a benzodiazepine derivative, the seven-membered ring adopts a distorted boat conformation. The crystal packing is controlled by inter-molecular N-H⋯O and C-H⋯O inter-actions.
منابع مشابه
Ethyl 2-{4-[(1,5-dibenzyl-2,4-dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl)methyl]-1H-1,2,3-triazol-1-yl}acetate
The reaction of 1,5-dibenzyl-3-propargyl-1,5-benzodiazepine-2,4-dione with ethyl azido-acetate in the presence of copper sulfate pentahydrate and sodium ascorbate leads to the formation of the title regioisomer, C(30)H(29)N(5)O(4), which features a phenyl-ene ring fused with a seven-membered diazepinyl ring. The latter ring adopts a boat conformation (with the methyl-triazolylacetate-bearing C ...
متن کامل5-Chloroacetyl-4-methyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one
In the title compound, C(12)H(13)ClN(2)O(2), the benzodiazepine ring adopts a distorted boat conformation. The carbonyl O atom and the Cl atom of the chloro-acetyl group are in a cis conformation. The crystal packing is controlled by inter-molecular C-H⋯O and N-H⋯O inter-actions.
متن کامل4-[(1,5-Dibenzyl-2,4-dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl)methyl]-1-n-octyl-1H-1,2,3-triazole
The reaction of 1,5-dibenzyl-3-propargyl-1,5-benzodiazepine-2,4-dione with 1-azido-n-octane in the presence of catalysts leads to the formation of the title compound, C(34)H(39)N(5)O(2), which features a phenyl-ene ring fused with a seven-membered diazepinyl ring. The latter ring adopts a boat conformation with the octyltriazolylmethyl-bearing C atom as the prow and the fused-ring C atoms as th...
متن کامل5-Dichloroacetyl-4-methyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one hemihydrate
There are two crystallographically independent organic mol-ecules in the asymmetric unit of the title compound, C(12)H(12)Cl(2)N(2)O(2)·0.5H(2)O. The benzodiazepine ring adopts a distorted boat conformation in both molecules. The crystal packing is controlled by N-H⋯O, C-H⋯O and O-H⋯O intra- and inter-molecular hydrogen bonds. A graph-set motif of R(3) (3)(14) dimer formation by a combination o...
متن کامل2,2,4-Trimethyl-5-(4-tolylsulfonyl)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine
In the title compound, C(19)H(24)N(2)O(2)S, the benzodiazepine ring adopts a distorted boat conformation. The S atom shows a distorted tetra-hedral geometry, with the O-S-O [119.16 (14)°] and N-S-C [107.48 (10)°] angles deviating significantly from ideal values. The crystal packing is controlled by C-H⋯O, N-H⋯O and C-H⋯π inter-actions.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 65 شماره
صفحات -
تاریخ انتشار 2009